400 years in the future, set in the year 2415, Aeon Flux is a mysterious assassin. Four centuries after a virus nearly decimated the human race, leaving only five million survivors in a utopian city called Bregna. Aeon is struggling to destroy the Goodchild regime led by its namesake, Trevor Goodchild, the ruler of Bregna and a descendant of the man who found a cure for the deadly virus. As instructed by the Handler, Aeon is assigned to assassinate Goodchild, but there are deeper secrets to be discovered, and conspiracies to be foiled.
In Germany, as graduate student Katie Armstrong researches cannibal killer Oliver Hagen for her thesis, she becomes obsessed with her subject and ultimately plunges into a lifestyle similar to Hagen's and the thousands of people like him.