This is the story of Willard Stiles who is a social misfit taking care of his ill and fragile but verbally abusive mother Henrietta in a musty old mansion that is also home to a colony of rats. Willard then finds himself constantly humiliated in front of his co-workers and is eventually fired by his cruel and uncaring boss, Mr. Frank Martin, a vicious man whose professional interest in Willard extends to a personal financial one.
Four astronauts have their lives changed forever, when they end up being hit by a cloud of cosmic radiation. Reed Richards now has the ability to stretch his body like elastic. Sue Storm (Alba) is now the invisible woman. Johnny Storm becomes the human touch and Ben Grimm becomes the 'Thing', a man made out of rock. But there is one problem. The journey's sponsor, Victor von Doom has also been affects and with full power, is a dangerous force which needs to be stopped, before it's too late.
Jonathan Ecks, an FBI agent, realizes that he must join with his lifelong enemy, Agent Sever, a rogue DIA agent with whom he is in mortal combat, in order to defeat a common enemy. That enemy has developed a "micro-device" that can be injected into victims in order to kill them at will.